Botulinum toxin in migraine.

nondystonic involuntary movements, including those excessive muscle contraction accompanying stroke, demyelinating disease, tremor, and cosmetic condition. Reported benefits in hyperhydrosis has proven that BTX can inhibit overactive non-motor as well as motor peripheral acetylcholine neurons. In addition to reducing muscle hyperactivity and spasm, BTX-A treatment often reduces the pain associated with cervical dystonia, achalasia, and rectal fissures. Evidence suggests that it may be beneficial in the treatment of chronic low back pain associated with muscle spasm. Recently it has been used in reducing drooling of saliva in Parkinson’s disease.